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What is Monkeypox Virus? Symptoms and Treatment

What is Monkeypox Virus? Symptoms and Treatment

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Liv Hospital Vadistanbul
Prof. MD. Gülgün Dilek Arman
Infectious Diseases and Clinical Microbiology
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15 August 2024
Article Content
  • What is Monkeypox Virus?
  • What are the Symptoms of Monkeypox Virus?
  • How Does Monkeypox Virus Spread?
  • What are the Risks of Monkeypox Transmission?
  • How to Protect Against Monkeypox Virus?
  • How is Monkeypox Virus Treated?
  • Frequently Asked Questions About Monkeypox Virus
  • Monkeypox virus is a double-stranded DNA virus belonging to the Poxviridae family. It causes symptoms similar to smallpox, typically transmitted from animals to humans, and is characterized by rashes and flu-like symptoms. Although it is most commonly found in the African continent, it can spread to other parts of the world through travel.

    What is Monkeypox Virus?

    Monkeypox virus (mpox) is a zoonotic virus that shows symptoms similar to smallpox, typically transmitted from animals to humans. This virus can cause symptoms such as rashes, fever, headache, and swelling of the lymph nodes. While it is most commonly seen in Central and West Africa, it can also spread to other regions of the world through travel. Monkeypox is a double-stranded DNA virus belonging to the Poxviridae family. Transmission usually occurs through direct contact with the skin lesions or bodily fluids of infected animals or individuals. Treatment is generally supportive, with no specific antiviral treatment available. Vaccination is the most effective way to prevent this disease.

    What are the Symptoms of Monkeypox Virus?

    Monkeypox symptoms typically begin with rashes and progress to flu-like symptoms. The most common symptoms of the disease include:

    • Rashes: The most characteristic feature of the disease is rashes that appear as itchy and painful blisters on the body. These rashes are usually found on the face, palms, soles, and genital area. The rashes evolve from red spots to fluid-filled blisters, then to pustules, and eventually crust over and heal.

    Stages of Rashes:

    1. Macule: Red, flat lesions appear.
    2. Papule: Lesions become raised and small fluid-filled blisters form.
    3. Pustule: Blisters dry up and form pustules.
    4. Crust: Pustules crust over and eventually fall off as the skin heals.
    • Fever: High fever is one of the initial common symptoms of the disease.
    • Headache: Severe headaches are another symptom.
    • Muscle Aches: Severe muscle aches, particularly in the back and legs.
    • Swollen Lymph Nodes: Noticeable swelling in lymph nodes under the arms, in the groin, and on the neck.
    • Fatigue: Severe tiredness and weakness.
    • Chills and Shivering: Sensation of cold and shivering.

    Monkeypox symptoms may vary in severity among individuals, and some people may not exhibit any symptoms. The course of the disease can depend on the individual's immune system and overall health.

    How Does Monkeypox Virus Spread?

    Monkeypox virus spreads primarily through direct contact with the skin lesions, bodily fluids, or respiratory droplets of infected animals or people. Transmission can occur from animals to humans and from humans to humans. The modes of transmission include:

    From Animals to Humans:

    • Contact with Infected Animals: The virus can be transmitted through direct contact with the blood, fluids, or tissues of infected animals, particularly rodents and primates.
    • Hunting and Meat Handling: The virus can be contracted through hunting, processing, or consuming meat from infected animals.
    • Virus Shed by Animals: The virus can spread from infected animals through contact with their feces, urine, fur, or skin.

    From Humans to Humans:

    • Bodily Fluids and Lesions: The virus can spread through direct contact with bodily fluids (blood, saliva, nasal discharge) or lesions of infected individuals.
    • Contact with Lesions: Direct contact with rashes, blisters, and scabs of infected individuals can lead to transmission.
    • Aerosols and Droplets: The virus can also spread through droplets released into the air by coughing, sneezing, or speaking, though this is less common compared to smallpox.

    Surface Transmission:

    • Surfaces and Objects: The virus can spread through surfaces or objects contaminated by infected individuals, especially items that have come into contact with rashes.

    What are the Risks of Monkeypox Transmission?

    The risks of monkeypox transmission depend on various factors including the modes of spread, interactions with infected individuals, and environmental conditions.

    1. Extended Contact: Close and prolonged contact with infected individuals increases the risk of transmission. Healthcare professionals, in particular, are at risk during close contact with infected individuals.
    2. Individuals with Weakened Immune Systems: People with weakened immune systems (e.g., HIV-positive individuals or those undergoing immunosuppressive treatment) are more susceptible to infections.
    3. Travel to Tropical Regions: People living in or traveling to tropical forest regions, where contact with infected animals is more likely, have a higher risk of exposure.

    How to Protect Against Monkeypox Virus?

    Monkeypox is a contagious disease typically seen in Africa. However, with recent global cases, protection methods have become increasingly important.

    Preventive Measures Against Monkeypox Virus:

    • Maintain Hygiene: Wash hands frequently with soap and water. Pay attention to hand hygiene after contact with sick individuals. Avoid touching skin lesions.
    • Practice Social Distancing: Avoid close contact with infected individuals. Stay away from crowded places.
    • Wear Masks: Use masks when in the same environment as infected individuals.
    • Do Not Share Personal Items: Avoid sharing personal items like towels, sheets, and cups.
    • Vaccination: Some countries have monkeypox vaccines. Consult your doctor regarding access to and efficacy of vaccines.
    • Healthy Lifestyle: Maintain a strong immune system through healthy eating and regular sleep.
    • Be Cautious While Traveling: If traveling to areas where the virus is common, take extra health precautions.

    How is Monkeypox Virus Treated?

    Treatment for monkeypox primarily aims to alleviate symptoms. Although there is no specific antiviral treatment, the following measures may help relieve symptoms and prevent complications:

    • Rest: Adequate sleep helps the body recover.
    • Fluid Intake: Drink plenty of fluids to prevent dehydration from fever and rashes.
    • Pain Relievers: Use pain relievers as recommended by your doctor to address fever and muscle aches.
    • Anti-Itch Creams: Apply creams prescribed by your doctor to reduce itching from rashes.
    • Antiviral Medications: Some antiviral drugs developed for smallpox may be effective against monkeypox. Use these medications under medical guidance.

    Treatment Goals:

    • Shorten the Duration of Illness
    • Reduce the Risk of Complications
    • Improve the Patient's Overall Condition

    Monkeypox generally resolves on its own, but complications may arise. Regular doctor visits are essential, and maintaining hygiene and limiting contact with others during treatment are crucial to prevent spread.

    Frequently Asked Questions About Monkeypox Virus

    Which Areas Are Most Affected?

    Monkeypox virus is most commonly seen in specific regions of Africa, particularly in tropical, rural areas of Central and West Africa. However, with increased travel, cases have been reported in various regions worldwide.

    What are the Symptoms of Monkeypox in Infants and Children?

    Symptoms in infants and children typically start with high fever, weakness, and loss of appetite, followed by rashes on the face, hands, feet, and body. The rashes evolve from red spots to blisters, pustules, and eventually crust over. In addition, infants may show signs of irritability, headache, muscle and joint pains, swollen lymph nodes, nausea, and vomiting.

    Is There a Vaccine for Monkeypox Virus?

    While some smallpox vaccines may provide partial protection against monkeypox, there is no specific vaccine solely for monkeypox. Consult with your doctor for information on available vaccines and their effectiveness.

    The World Health Organization (WHO) provides information about monkeypox virus, manages global health risks, and takes measures to control outbreaks. Adhering to these measures is vital for both personal and public health.

    * Liv Hospital Editorial Board has contributed to the publication of this content .
    * Contents of this page is for informational purposes only. Please consult your doctor for diagnosis and treatment. The content of this page does not include information on medicinal health care at Liv Hospital .
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