Handan Haydaroğlu Şahin

• Gaziantep University Faculty of Medicine (Hematology) (2010-2016)
• Gaziantep University Faculty of Medicine (Internal Medicine) (2004-2010)
• Istanbul University Cerrahpasa Faculty of Medicine (1998-2004)

• Liv Hospital Gaziantep (2023 - )
• Gaziantep University, Faculty of Medicine, Department of Hematology (2010-2023)
• Şehitkamil State Hospital (2010-2010)
• Gaziantep University, Faculty of Medicine, Department of Internal Medicine (2004-2010)

*(Science Citation Index http://science.thomsonreuters.com)
**(Science Citation Index Expanded, http://science.thomsonreuters.com)

A1*. Yanardag Acık D, Yilmaz M, Sahin HH, Sayıner Z, Koruk I, Tiryaki O, Okan V, Pehlivan M. Management of Chenopodium polyspermum Toxicity With Plasma Exchange and Hemodialysis. J Clin Apher. 2012 Nov; 27(5):278-81. doi: 10.1002/jca.21238.

A2*. Selvi N, Kaymaz BT, Sahin HH, Pehlivan M, Aktan C, Dalmızrak A, Inalpolat E, Kosova B, Yılmaz M, Okan V, Saydam G. Two cases with hypereosinophilic syndrome shown with real-time PCR and responding well to imatinib treatment. Mol Biol Rep. 2013 Feb; 40(2):1591-7. doi: 10.1007/s11033-012-2207-6.

A3**. Sahin F, Saydam G, Cömert M, Uz B, Yavuz AS, Turan E, Yönal I, Atay H, Keltikli E, Turgut M, Pehlivan M, Akay MO, Gürkan E, Paydaş S, Kahraman S, Demirkan F, Kırkızlar O, Akpınar S, Pamuk GE, Demir M, Özbaş HM, Sönmez M, Gültürk M, Salihoğlu MGA, Eşkazan AE, Ar C, Şahin HH, Öngören S, Başlar Z, Aydın Y, Yenere MN, Tüzüner N, Ferhanoğlu B, Haznedaroglu IC, İlhan O, Soysal T. Turkish Chronic Myeloid Leukemia Study: Retrospective Sectional Analysis of CML Patients. Turk J Haematol. 2013 Dec;30(4):351-8. doi: 10.4274/tjh.2013.0151.

A4**. Pehlivan M, Sahin HH, Ozdilli K, Onay H, Ozcan A, Ozkinay F, Pehlivan S. Gene Polymorphisms and Febrile Neutropenia in Acute Leukemia-No Association with IL-4, CCR-5, IL-1RA, but the MBL-2, ACE, and TLR-4 Are Associated with the Disease in Turkish Patients: A Preliminary Study. Genet Test Mol Biomarkers. 2014 Jul;18(7):474-81. doi: 10.1089/gtmb.2014.0004.

A5**. Pehlivan M, Sahin HH, Pehlivan S, Ozdilli K, Kaynar L, Oguz FS, Sever T, Yilmaz M, Eser B, Ogret YD, Kis C, Okan V, Cetin M, Carin M. Prognostic Importance of Single-Nucleotide Polymorphisms in IL-6, IL-10, TGF-β1, IFN-γ, and TNF-α Genes in Chronic Phase Chronic Myeloid Leukemia. Genet Test Mol Biomarkers. 2014 Jun;18(6):403-9. doi: 10.1089/gtmb.2014.0011.

A6**. Karaoğlan İ, Ekşi F, Haydaroğlu Şahin H, Pehlivan M, Tekin Şahin S, Keçik Boşnak V, Bilici M, Namıduru M, Karslıgil T. Two cases of visceral leishmaniasis from Kahramanmaraş, Turkey. Mikrobiyol Bul. 2015 Apr;49(2):295-8. 

A7** . Sönmez A, Eksi F, Pehlivan M, Haydaroglu Sahin H. Investigating the presence of fungal agents in febrile neutropenic patients using different microbiological, serological, and molecular methods. Bosn J Basic Med Sci. 2015 Jul 27;15(3):40-7. doi: 10.17305/bjbms.2015.409.

A8**. Boşnak VK, Karaoğlan İ, Sahin HH, Namiduru M, Pehlivan M, Okan V, Mete AÖ. Evaluation of patients diagnosed with fascioliasis: A six-year experience at a university hospital in Turkey. J Infect Dev Ctries. 2016 Apr 28;10(4):389-94. doi: 10.3855/jidc.6681.

A9*. Tomatir AG, Pehlivan S, Sahin HH, Balci SO, Budeyri S, Pehlivan M. Q192R and L55M Polymorphisms of Paraoxonase 1 Gene in Chronic Myelogenous Leukemia and Chronic Lymphocytic Leukemia. Anticancer Res. 2015 Sep;35(9):4807-12.

A10* . Haydaroglu H, Oguzkan Balci S, Pehlivan S, Ozdilli K, Gundogan E, Okan V, Nursal AF, Pehlivan M. Effect of Cytokine Genes in the Pathogenesis and on the Clinical Parameters for the Treatment of Multiple Myeloma. Immunol Invest. 2017 Jan;46(1):10-21. doi: 10.1080/08820139.2016.1208219.
A11**. Nursal AF, Pehlivan M, Sahin HH, Pehlivan S. The Associations of IL-6, IFN-γ, TNFα, IL-10, and TGF-β1 Functional Variants with Acute Myeloid Leukemia in Turkish Patients. Genet Test Mol Biomarkers. 2016 Sep;20(9):544-51. doi: 10.1089/gtmb.2016.0036.
A12**. Pehlivan M, Tomatir AG, Nursal AF, Sahin HH, Pehlivan S. The Endothelial Nitric Oxide Synthase Gene Variants as a Risk Factor for Chronic Lymphocytic Leukemia. International Journal of Hematology and Oncology. Number: 2 Volume: 27 Year: 2017 doi: 10.4999/uhod.171703.

A13**. Zengin O, Okan V, Ozkur A, Sayiner ZA, Sahin HH, Yilmaz M, Pehlivan M. The Relationship of Frequency and Intensity of Bleeding with Hemophilic Arthropathy in Hemophilia Patients, Radiological Assesment and Socio-Economic Impacts of the Arthropathy. International Journal of Hematology and Oncology (UHOD) 1:25;32-37, 2015.

A14*. Haydaroglu Sahin H, Mete A, Pehlivan M. Neurolymphomatosis in non-Hodgkin lymphoma with cranial multineuritis: A case report. Medicine (Baltimore). 2018 Apr;97(15):e0303. doi: 10.1097/MD.0000000000010303.

A15*. Ekşi F, Karsligil T, Gündeş I, Sağlam M, Kirik MP, Büdeyri MS, Haydaroğlu Şahin H, Pehlivan M. Investigation of BK Virus by Real-Time Polymerase Chain Reaction in Patients With Allogeneic Bone Marrow Transplantation. Transplant Proc. 2018 Jun;50(5):1510-1513. doi: 10.1016/j.transproceed.2017.12.056.

A16**. Özdöver AC, Gündeş İ, Kirik MP, Haydaroğlu Şahin H, Sucu M, Pehlivan M. Evaluation of Cardiac Parameters in Bone Marrow Transplant Patients: Effect of pulmonary artery pressure on survival. Turk J Haematol. 2019 Feb 7;36(1):19-24. doi: 10.4274/tjh.galenos.2018.2018.0015.

A17**. Cekdemir D, Guvenc S, Ozdemirkiran F, Eser A, Toptas T, Ozkocaman V, Haydaroglu Sahin H, Ermis Turak E, Esen R, Comert M, Sadri S, Aslaner M, Uncu Ulu B, Karakus A, Selim Bapur D, Alacacioglu I, Aydin D, Tekinalp A, Namdaroglu S, Ceran F, Tarkun P, Kiper D, Cetiner M, Yenerel M, Demir AM, Yilmaz G, Terzi H, Atilla E, Malkan UY, Acar K, Ozturk E, Tombak A, Sunu C, Salim O, Alayvaz N, Sayan O, Ozan U, Ayer M, Gokgoz Z, Andic N, Kizilkilic E, Noyan F, Ozen M, Pepedil Tanrikulu F, Alanoglu G, Ozkan HA, Aslan V, Cetin G, Akyol Erikci A, Deveci B, Ersoy Dursun F, Dermenci H, Aytan P, Gunduz M, Karakus V, Ozlu C, Demircioglu S, Akay Yanar OM, Ozatli D, Undar L, Tiftik EN, Turkoz Sucak AG, Haznedaroglu I, Ozcan M, Sencan M, Tombuloglu M, Ozet G, Bilgir O, Turgut B, Ozcan MA, Payzın KB, Sonmez M, Ayyildiz O, Dal MS, Ertop S, Turgut M, Soysal T, Kaya E, Unal A, Pehlivan M, Atagunduz I, Tuglular Firatli T, Saydam G, Diz Kucukkaya R. A multi-centric study on the efficacy of eltrombopag in management of refractory chronic immune thrombocytopenia. Turk J Haematol. 2019 Nov 18;36(4): 230-237. doi: 10.4274/tjh.galenos.2019.2018.0307.

A18*. Haydaroglu Sahin H. Can the prognosis of mantle cell lymphoma be predicted by simple CBC counts?. Medicine (Baltimore). 2019 Jul;98(30):e16180. doi: 10.1097/MD.0000000000016180.
A19**. Soyer Nur , Mehmet Gunduz, Emre Tekgunduz , Burak Deveci , Hakan Ozdogu, Handan Haydaroglu Sahin,et al. "Incidence and risk factors for hepatic sinusoidal obstruction syndrome after allogeneic hematopoietic stem cell transplantation: A retrospective multicenter study of Turkish hematology research and education group (ThREG)." Transfusion and Apheresis Science 59.4 (2020): 102827.
A20*. Elboga U, Sahin E, Cayirli YB, Okuyan M, Aktas G, Haydaroglu Sahin H, Dogan I, Kus T, Akkurd DM, Cimen U, Mumcu V, Kilbas B, Celen YZ. Comparison of [68Ga]-FAPI PET/CT and [18F]-FDG PET/CT in Multiple Myeloma: Clinical Experience. Tomography. 2022 Feb 1;8(1):293-302. doi: 10.3390/tomography8010024. 
A21. M.A. Ucar, G. Ozet, M.B. Koyuncu3, M. Sonmez, O. Akıdan, M. Aylı, M. Yıldırım, M. Pehlıvan, D.M. Akkurd, H. Sahın, B. Guvenc, V. Okan, E.N. Tıftık, A. Akdenız, H.D. Dıncyurek, A.K. Gunes, S. Dagdas, H.İ. Acar, H.K. Ucar, A. Tombak. "Real world results of venetoclax combined with hypomethylating agents in relapsed/refractory AML." Eur Rev Med Pharmacol Sci 25.21 (2021): 6557-6565.

B. Papers presented at international scientific meetings and published in Proceedings:

B1.Yanardağ Açık D, Sayıner ZA, Yılmaz M, Akarsu E, Ozsan M, Koruk I, Ercan S, Haydaroglu Sahin H, Okan V, Pehlivan M. Therapeutic plasma exchane in patients with hypertriglyceridemia-induced pancreatitis: case series. Transfusion and Apheresis Sience Volume 47, Supplement 1, Pages 54. Semptember 13-16 2012, İstanbul/Turkey. Abstracts of the 14th İnternational congress of the World apheresis. Doi: 10.1016/S1473-0502(12)70107-6. Poster Bildiri.

B2. Mehmet Yılmaz, Serhat İnalöz, Salih Subarı, Mesut Özkaya, Didar Yanardağ Açık, Handan Haydaroğlu Şahin, Özhan Uygun, Mustafa Pehlivan, Vahap Okan. Analysis of the efficacy and side effects of bexarotene in the treatment of mycosis fungoides: a report of five cases. 4th International Congress on Leukemia – Lymphoma – Myeloma. May 22 – 25 2013, Istanbul/Turkey. Poster Bildiri.

  B3. Haciboncuk P, Yilmaz M, Soylu G, Gundogan E, Yanardag Acık D, Okan V, Pehlivan M, Sahin HH, Kul S, Sarı I. Investigation On The Frequency Of Cd10, Cd30, Bcl-2, Bcl-6, Mum-1, P53, Ki-67 And Impact To The Prognosis In Patients With Diffuse Large B-Cell Lymphoma; PP-028. Vth International Eurasian Hematology Congress Leukemia Research S1–S65. October 15-19 2014, Antalya/Turkey. Poster Bildiri.

  B4. Sahin HH, Pehlivan S, Pehlivan M, Kul S, Okan V, Oguzkan Balci S. MiR-17-92 gene cluster may be prognostic biomarker in multiple myeloma? The Best Five Abstracts Awards This year five registrants who submit high-quality abstracts will be awarded. 5th International Congress on Leukemia Lymphoma Myeloma (ICLLM); PS-056. May 21-23 2015, İstanbul/Turkey. Poster Bildiri. 

  B5. Pehlivan M, Tomatir A.G., Nursal A.F., Sahin H.H., Pehlivan S. Importance of Endothelial Nitric oxide synthase gene variants in patients with Chronic Lymphocytic Leukemia. International conference on aging and Hematological malignancies: Biology and therapy; P:05. March 11-13 2016, Athens/Greece. Poster Bildiri.

   B6.  Tomatir A.G., Pehlivan S, Sahin H.H., Balci SO., Budeyri S, Pehlivan M. Q192R and L55M polymorphisms of paraoxonase 1 gene in Chronic Myelogenous Leukemia and Chronic Lymphocytic Leukemia. International conference on aging and Hematological malignancies: Biology and therapy; P:06. March 11-13 2016, Athens/Greece. Poster Bildiri.

    B7. Feyda Nursal A., Pehlivan M., Haydaroglu Sahin H., Pehlivan S. The associations of IL- 6, IFN-γ, TNF-α, IL-10, and TGF-β1functional variants with Acute Myeloid Leukemia in Turkish patients. International conference on aging and Hematological malignancies:Biology and therapy; P:04. March 11-13 2016, Athens/Greece. Poster Bildiri.

    B8. Handan Haydaroğlu Şahin, Sibel Oğuzkan Balcı, Sacide Pehlivan, Kürşat Özdilli, Erdal Gündoğan, Vahap Okan, Ayşe Feyda Nursal, Mustafa Pehlivan. Effect of Cytokine genes in the pathogenesis and on the clinical parameters for the treatment of Multiple Myeloma. 6th International Congress on Leukemia – Lymphoma – Myeloma. May 11 – 13 2017, Antalya/Turkey. Poster Bildiri.

    B9. Haydaroğlu Şahin H, Pehlivan M. Autologous Peripheral Stem Cell Transplantation with R/BEAM protocol after Modified R/IDARAM/ RT in DLCL with CNS involvement: A single‐center experience. 43rd Annual Meeting of the European-Group-for-Blood-and-Marrow-Transplantation (EBMT) Poster; B081. March 26-29 2017, Marseille/France. http://www.ebmt2017.org/poster-abstracts. Poster Bildiri.

    B10. Pehlivan M, Kırık MP, Haydaroglu Sahin H, Gundes I. Effectivity of a fludarabine based conditioning regimen in allogenic hematopoietic stem cell tranplantation for patients with severe aplastic anemia and over twenty years old. 43rd Annual Meeting of the European-Group-for-Blood-and-Marrow-Transplantation (EBMT) Poster; B368. March 26-29 2017, Marseille/France. http://www.ebmt2017.org/poster-abstracts. Poster Bildiri.

    B11. Gündeş I, Ekşi F, Pehlivan M, Kırık MP, Haydaroğlu Şahin H, Altunpınar S, Özyürük E, Zer Y. Amebiazis in Hematopoietic Stem Cell Transplantation: An Endemic Region Analysis. 43rd Annual Meeting of the European-Group-for-Blood-and-Marrow-Transplantation (EBMT) Poster; B361. March 25-29 2017, Marseille/France. http://www.ebmt2017.org/poster-abstracts. Poster Bildiri.

     B12. Soyer N, Gündüz M, Tekgündüz E, Haydaroglu Sahin H, Yıldızhan E, Okay M, Kuku I, Yönal Hindilerden I, Topcuoglu P, Altuntaş F, Pehlivan M, Unal A, Goker H, Erkurt MA, Kalayoglu Besısık S, Vural F. Incidence and risk factors for hepatic sinusoidal obstruction syndrome after allogeneic hematopoietic stem cell transplantation: a retrospective multicenter study of Turkish Hematology Research and Education Group (ThREG). 43rd Annual Meeting of the European-Group-for-Blood-and-Marrow-Transplantation (EBMT) Poster; A409. March 26-29 2017, Marseille/France. http://www.ebmt2017.org/poster-abstracts. Poster Bildiri.
 
     B13. Sevindik OG, Solmaz ŞM, Pehlivan M, Hacioglu S, Yalniz FF, Ozkocaman V, Arat M, Turgut M, Ozcan M, Arslan O, Sonmez M, Aydin Y,  Haydaroğlu Şahin H, Dogu HM, Tombak A, Bayar B, Yaradilmiş İ, Ozsan GH. Real-word data in relapsed refractory myeloma patients with Carfilzomib, a multicenter Turkish experience. 6th international Congress on Leukemia, Lymphoma, Myeloma. May 11-13 2017, Antalya/Turkey. Poster Bildiri.
 
    B14. Sarıfakılıoğulları Aliye Serpil, Kırık Melya Pelin, Durusoy Salih Sertaç, Haydaroğlu Şahin Handan, Gündeş İlknur, Pehlivan Mustafa. Use of Eltrombopag in Patients with Platelet Engraftment Failure Following Second Allogeneic Peripheral Stem Cell Transplantation: Three case reports and Literature Review. Poster; P508. 44. Annual Meeting of The European Society for Blood and Marrow Transplantation (EBMT). March 18-21 2018, Lisbon/Portekiz. Poster Bildiri.

   B15. Haydaroğlu Şahin Handan. Pankreas, Safra Kesesi ve Safra Yolları Kanserlerinde RHO-KİNAZ Gen Polimorfizmi ile Metastaz arasındaki ilişkinin araştırılması. 5th International Congresson Mathematics, Engineering, Natural and Medical Sciences. November 22-25, 2018. Gaziantep/Turkey. Sözlü Sunum.

   B16. Haydaroğlu Şahin Handan. Hematolojik Malignitelerde Prokalsitonin Düzeyi ve C-Reaktif Protein Düzeyinin Diagnostik Önemi. Zeugma I. Uluslararası Multidisipliner Çalışmalar Kongresi. Semptember 13-16, 2018. Gaziantep/Turkey. Sözlü Sunum.

  B17. Durusoy Salih Sertaç, Haydaroğlu Şahin Handan, Okan Vahap, Pehlivan Mustafa. Late diagnosis in Syrian immigrant patient: thiamine-responsive megaloblastic anemia syndrome. 9th International Eurasian Hematology Oncology Congress (EHOC) Location. October 17-20, 2018. Istanbul/Turkey. Poster Bildiri.

  B18. Elif Melis Baloğlu Akyol, Handan Haydaroğlu Şahin, Fahriye Ekşi, Sadettin Öztürk, İlknur Gündeş, Melya Pelin Kırık, Müzeyyen Selin Büdeyri, Mustafa Pehlivan. Clinical Course of Cytomegalovirus Infection, its Impact on Hematopoietic Stem Cell Transplantation and Efficacy of Preemptive Antiviral Therapy. Poster; P499. 44. Annual Meeting of The European Society for Blood and Marrow    Transplantation (EBMT). March 18-21 2018, Lisbon/Portekiz. Poster Bildiri.

B19. Aliye Serpil Sarifakiogullari, Salih Sertac Durusoy, Handan Haydaroglu Sahin, Mustafa Pehlivan. Autologous Peripheral Stem Cell Transplantation Treatment in Relapsed/refractory Hodgkin Lymphoma Patient: One Centre Experience. Poster; P608. 44. Annual Meeting of The European Society for Blood and Marrow Transplantation (EBMT). March 18-21 2018, Lisbon/Portekiz. Poster Bildiri.

B20. Ali Caner Ozdover, Ilknur Gundes, Melya Pelin Kirik, Handan Haydaroglu Sahin, Murat Sucu, Mustafa Pehlivan. Evaluation of Cardiac Parameters in Bone Marrow Transplant Patients: Effect of pulmonary artery pressure on survival. Poster; P471. 44. Annual Meeting of The European Society for Blood and Marrow Transplantation (EBMT). March 18-21 2018, Lisbon/Portekiz. Poster Bildiri.

B21. K. Ozdilli, M. Pehlivan, F. Oğuz Savran, H. Issever,  H. Haydaroğlu Sahin, S. Pehlivan. XRCC4 gene (Intron 3 VNTR) polymorphism predisposition to chronic phase chronic myeloid leukemia (CML) and XRCC1 gene (399) polymorphism in associated with event-free survival in CML treated with imatinib in Turkish population. P12.038-M. Abstract Book, Volume 22 Supplement 1 M. European Human Genetics Conference 2014. May 31 - June 3 2014 Milan/Italy. Poster Bildiri.

B22. Ceren Tekin, Sibel Bayıl Oğuzkan, Mehmet Özaslan, Handan Haydaroğlu, Selin Büdeyri, Mustafa Pehlivan. Investigation of the MDM2 Gene polymorphism in patients with acute myeloid leukemia. Poster; PP-31. 1st International Cell Death Research Congress. May 4-7 2016, Izmir/Turkey. Poster Bildiri

• Member of Turkish Society of Hematology (2017-current)
• Hematology Specialty Association (2018-present)

• Best Research Award; 1st National Medical Mycology Congress (2014)
• TURKBA AWARD; 41st National Hematology Congress (2015)
• Best Paper Award; II. International Congress of Experimental Hematology (2015)
• The Best Abstract Award; 5th International Congress on Leukemia Lymphoma Myeloma (2015)